Project Manager II: Late Phase Oncology; ISR/CO Study Manager (Sponsor Dedicated/ US Remote)

Project Manager II: Late Phase Oncology; ISR/CO Study Manager (Sponsor Dedicated/ US Remote)

Syneos Health® is a leading fully integrated biopharmaceutical solutions organization built to accelerate customer success. We translate unique clinical, medical affairs and commercial insights into outcomes to address modern market realities.

Our Clinical Development model brings the customer and the patient to the center of everything that we do. We are continuously looking for ways to simplify and streamline our work to not only make Syneos Health easier to work with, but to make us easier to work for.

Whether you join us in a Functional Service Provider partnership or a Full-Service environment, you’ll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to accelerate the delivery of therapies, because we are passionate to change lives.

Discover what our 29,000 employees, across 110 countries already know:

WORK HERE MATTERS EVERYWHERE

Why Syneos Health

• We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program.
• We are committed to our Total Self culture – where you can authentically be yourself. Our Total Self culture is what unites us globally, and we are dedicated to taking care of our people.
• We are continuously building the company we all want to work for and our customers want to work with. Why? Because when we bring together diversity of thoughts, backgrounds, cultures, and perspectives – we’re able to create a place where everyone feels like they belong.

Job Responsibilities

Project Manager II: Late Phase Oncology; ISR/CO Study Manager (Sponsor Dedicated/ US Remote)

Make an Impact Where It Matters Most

Are you an experienced ISR/CO Study Manager ready for a role where your expertise directly accelerates meaningful oncology research? At Syneos Health, you’ll step into a high‑visibility, sponsor‑dedicated position supporting a large portfolio of Investigator Sponsored Research (ISR) and collaborative (CO) studies. You’ll partner closely with Medical Affairs and principal investigators to drive studies to completion and support their path to publication.

This isn’t traditional project management—this is customer‑facing scientific study management at scale, where strong communication, organization, and oncology expertise truly matter.

What You’ll Own & Lead:

🔹 ISR/CO Study Oversight & Execution

• Manage a high volume of global ISR and collaborative studies , ensuring compliance, scientific integrity, and timely progression.

• Serve as the primary operational contact for principal investigators and study teams, providing ongoing support from start‑up through completion.

• Ensure accurate tracking of study status, milestones, documentation, and deliverables across the ISR/CO portfolio.

• Partner with Medical Affairs to facilitate study progress , troubleshoot issues, and remove barriers to execution.

• Support investigators through the publication process , including data requests, review timelines, and coordination with internal stakeholders.

🔹 Financial & Risk Management

• Oversee study budgets, financial tracking, and forecasting for assigned ISR/CO programs.

• Monitor potential risks related to funding, operations, timelines, and compliance; escalate and mitigate proactively.

• Review and approve site/vendor invoices and support client billing with accuracy and accountability.

🔹 Client, Investigator & Cross‑Functional Partnership

• Represent Syneos Health as a key point of contact in this high‑visibility, customer‑facing role .

• Build strong working relationships with Medical Affairs, sponsors, and investigators to ensure alignment and clarity of expectations.

• Lead internal/external meetings with confidence—driving communication, organization, and follow‑through.

🔹 Training, Knowledge & Thought Support

• Participate in protocol‑specific onboarding and study‑related training.

• Continue to deepen your expertise in oncology and late‑phase research.

• Share knowledge and best practices with peers and cross‑functional teams to elevate study execution standards.

What You Bring:

• MUST HAVE: Prior experience managing ISR/CO studies within a pharmaceutical or CRO environment.

• Oncology experience required , ideally late‑phase.

• Strong understanding of ICH GCP, ethics, regulatory expectations, and clinical research operations.

• Exceptional communication, organization, and time management skills —this role is highly visible and investigator‑facing.

• Ability to manage multiple simultaneous studies, prioritize effectively, and work independently.

• Proficiency in MS Office and comfort working in a dynamic, fast‑paced environment.

Why This Role Rocks:

✨ A uniquely collaborative environment where your voice and expertise are valued.
✨ Opportunities for ongoing learning, mentorship, and career growth.
✨ High visibility with both sponsor and investigators.
✨ Direct impact on meaningful oncology research and scientific publications that reach patients worldwide.

At  Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance. We reward and recognize our people by providing valuable benefits and a quality-of-life balance. The benefits for this position may include a company car or car allowance, Health benefits to include Medical, Dental and Vision, Company match 401k, eligibility to participate in Employee Stock Purchase Plan, Eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time. Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work. Syneos complies with all applicable federal, state, and municipal paid sick time requirements.

Salary Range:

$95,000.00 - $175,700.00

The base salary range represents the anticipated low and high of the Syneos Health range for this position. Actual salary will vary based on various factors such as the candidate’s qualifications, skills, competencies, and proficiency for the role.

Get to know Syneos Health

Over the past 5 years, we have worked with 94% of all Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 Studies across 73,000 Sites and 675,000+ Trial patients.

No matter what your role is, you’ll take the initiative and challenge the status quo with us in a highly competitive and ever-changing environment. Learn more about Syneos Health.

Additional Information

Tasks, duties, and responsibilities as listed in this job description are not exhaustive. The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities. Equivalent experience, skills, and/or education will also be considered so qualifications of incumbents may differ from those listed in the Job Description. The Company, at its sole discretion, will determine what constitutes as equivalent to the qualifications described above. Further, nothing contained herein should be construed to create an employment contract. Occasionally, required skills/experiences for jobs are expressed in brief terms. Any language contained herein is intended to fully comply with all obligations imposed by the legislation of each country in which it operates, including the implementation of the EU Equality Directive, in relation to the recruitment and employment of its employees. The Company is committed to compliance with the Americans with Disabilities Act, including the provision of reasonable accommodations, when appropriate, to assist employees or applicants to perform the essential functions of the job.