Clinical Trial Liaison

ICON plc
North Carolina

Clinical Trial Liaison

ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development.

As a Clinical Trial Liaison at ICON, you will design and analyze clinical trials, interpreting complex medical data, and contribute to the advancement of innovative treatments and therapies.

What you will do:

Clinical Investigator Management

  • Accountable for the full spectrum of investigator engagement from identification and qualification through enrollment, and support database lock, and study closeout

  • Serve as a clinical trial scientific ambassador, ensuring investigators deeply understand protocol intent, scientific rationale, and patient eligibility requirements

  • Develop and sustain strategic, high-trust relationships with investigators that span trials and therapeutic areas

  • Influence enrollment by co-creating tailored recruitment strategies aligned with site capabilities, patient population realities, and study objectives

  • Proactively find opportunities to reach new patients, accelerate enrollment and increase impact at priority sites, including for example, novel site models, community-based research initiatives etc

  • Capture and elevate critical insights from sites to optimize feasibility, protocol design, and study conduct

Clinical Trial Management

  • Lead site-level strategy and risk planning to ensure strong and predictable enrollment and data delivery

  • Leverage performance metrics to anticipate issues, intervene decisively, and maintain momentum toward clinical milestones

  • Drive inspection readiness as a continuous discipline across sites

  • Collaborate across functions and with vendor partners to resolve operational barriers, ensuring delivery with speed and quality

  • Maintain advanced understanding of local treatment paradigms and standard of care to influence strategic country/site selection and protocol localization

  • Provide oversight and quality assurance for vendor monitoring, escalating risks proactively

  • Where applicable, lead end-to-end management of Post-Marketing Safety Studies in compliance with local regulations

  • Business Management and Engagement

  • Cultivate a portfolio of strategically aligned, high-impact investigators who consistently prioritize client trials

  • Enable an exceptional investigator experience by being a responsive, knowledgeable, and valued scientific partner

  • Collaborate cross-functionally (e.g., Medical, Clinical, Study Delivery) to align on trial and site priorities, troubleshooting challenges with urgency and creativity

  • Conduct data-informed site prospecting and prioritization, contributing to trial competitiveness and regional strategic execution

  • Maintain scientific fluency and therapeutic expertise to lead meaningful, solutions-focused discussions with site personnel

  • Act as a key liaison between field teams, vendors, and investigators, ensuring alignment, shared purpose, and continuous knowledge transfer

  • Partner closely with field team colleagues to elevate the investigator and site experience, ensuring seamless collaboration and improving enrollment outcomes and Investigator relationships


You are:

  • Bachelor’s degree or equivalent; strong preference for scientific, clinical, or health-related fields

  • Minimum 5 years of experience in clinical research or pharmaceutical industry with experience directly interacting with or working with HCPs and clinical sites

  • Open to up to 60-80% travel during peak times (travel will vary)

  • Oncology experience required (Breast/Gyn experience preferred)

  • Location: Mid-Atlantic, Southeast Region

What ICON can offer you:
Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent.

In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.

Our benefits examples include:

  • Various annual leave entitlements
  • A range of health insurance offerings to suit you and your family’s needs.
  • Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
  • Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family’s well-being.
  • Life assurance
  • Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others.

Visit our careers site to read more about the benefits ICON offers.

At ICON, inclusion & belonging are fundamental to our culture and values. We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here

Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there’s every chance you’re exactly what we’re looking for here at ICON whether it is for this or other roles.

Are you a current ICON Employee? Please click here to apply

Posted 2026-07-20

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