Principal Investigator - Dermatology North Carolina

Job Title: Clinical Principal Investigator (Dermatology, PRN)
Location : Concord, NC
Engagement : PRN / Contract (approx. 5–10 hours per week)

Overview

The Clinical Principal Investigator (PI) provides overall medical leadership and oversight for dermatology clinical research studies conducted at the site. This position ensures trials are executed in accordance with ICH-GCP, FDA, and institutional standards , maintaining participant safety and scientific integrity. The PI serves as the primary liaison between the sponsor, CRO, and study staff.

Responsibilities

• Provide medical and regulatory oversight for dermatology-focused clinical studies.
• Review and approve study protocols, informed-consent forms, and case report documentation.
• Evaluate participant eligibility, perform clinical assessments, and ensure patient safety throughout the study.
• Supervise sub-investigators, coordinators, and site staff to ensure GCP compliance.
• Oversee investigational product management and documentation.
• Communicate with sponsors, IRBs, and auditors; ensure inspection readiness.
• Review and sign adverse-event reports, CRFs, and final study reports.

Qualifications

• MD (or equivalent) with an active, unrestricted NC medical license .
• Board certification in Dermatology strongly preferred.
• Minimum 5 years of experience as a PI or Sub-Investigator in dermatology or related clinical research.
• Comprehensive knowledge of ICH-GCP and FDA regulations .
• Strong leadership, communication, and clinical judgment skills.

System One, and its subsidiaries including Joulé, ALTA IT Services, TeamPeople, and Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.

System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.