Principal Product Manager

Principal Product Manager

Syneos Health® is a leading fully integrated biopharmaceutical solutions organization built to accelerate customer success. We translate unique clinical, medical affairs and commercial insights into outcomes to address modern market realities.

Our Clinical Development model brings the customer and the patient to the center of everything that we do. We are continuously looking for ways to simplify and streamline our work to not only make Syneos Health easier to work with, but to make us easier to work for.

Whether you join us in a Functional Service Provider partnership or a Full-Service environment, you’ll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to accelerate the delivery of therapies, because we are passionate to change lives.

Discover what our 29,000 employees, across 110 countries already know:

WORK HERE MATTERS EVERYWHERE

Why Syneos Health

• We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program.
• We are committed to our Total Self culture – where you can authentically be yourself. Our Total Self culture is what unites us globally, and we are dedicated to taking care of our people.
• We are continuously building the company we all want to work for and our customers want to work with. Why? Because when we bring together diversity of thoughts, backgrounds, cultures, and perspectives – we’re able to create a place where everyone feels like they belong.

Job Responsibilities

The Principal Product Manager drives enterprise-level product strategy and outcomes for healthcare and life sciences products and capabilities, which may include software, technology-enabled, or data-enabled solutions. This role defines long-term product vision and strategy across multiple products or platforms, partners closely with executive leadership, and influences key business decisions through product insights. Operating with broad autonomy, the Principal Product Manager leads through influence, sets product standards and best practices, and ensures product investments deliver measurable customer and business impact in a regulated environment.

JOB RESPONSIBILITIES

• Define and communicate long-term product vision and strategy across a portfolio of products, platforms, or capabilities aligned with business objectives.

• Partner with executive leadership to shape business strategy through product insights, market intelligence, and customer understanding.

• Ensure alignment of product goals across teams and functions, including engineering, data science, design, commercial, and operations.

• Conduct in-depth market, customer, and competitive analysis to identify opportunities, risks, and emerging trends.

• Oversee the full product lifecycle across multiple products or capabilities, from ideation through growth, optimization, and sunset.

• Act as a senior voice of the customer, ensuring customer needs, regulatory considerations, and usability are reflected in product strategy.

• Define and monitor success metrics and key performance indicators (KPIs) at the product and portfolio level to drive outcomes-based decision-making.

• Identify strategic, operational, and regulatory risks and develop mitigation strategies to ensure successful product delivery and adoption.

• Influence prioritization and investment decisions to maximize customer value and return on investment.

• Lead through influence by coaching and mentoring Product Managers and Senior Product Managers, and by establishing product best practices.

• Drive consistency and scalability across products by defining frameworks, standards, and reusable capabilities.

• Build and maintain strategic partnerships with internal teams, customers, vendors, and external partners that enhance the overall product value proposition.

• Represent the product organization with key customers, partners, and industry forums as a product thought leader, as appropriate.

QUALIFICATIONS

Education & Experience

• Bachelor’s degree (BS/BA) in Information Systems, Management, Statistics, Computer Science, Data Science, Engineering, or a related field.

• Extensive experience leading product strategy and delivery for complex software, technology-enabled, or data-enabled products in healthcare, life sciences, or other regulated industries.

Product Strategy & Leadership

• Demonstrated ability to define and evolve long-term product vision and strategy across multiple products or platforms.

• Proven experience influencing executive stakeholders and driving alignment across complex, cross-functional organizations.

• Strong business acumen with experience developing product investment cases and prioritization frameworks.

Market, Customer & Industry Insight

• Deep understanding of customer needs, industry trends, and competitive landscapes within healthcare or life sciences.

• Ability to anticipate regulatory, compliance, and market changes and proactively adapt product strategy.

Data & Technical Fluency

• Strong product-level understanding of technology and data concepts sufficient to guide strategic decisions and evaluate tradeoffs.

• Ability to partner effectively with engineering, data science, and architecture leaders without requiring hands-on technical implementation.

Communication & Influence

• Exceptional verbal and written communication skills, with the ability to convey complex concepts clearly to executive and non-technical audiences.

• Strong ability to lead through influence, build consensus, and navigate ambiguity.

Ways of Working

• Strategic, outcomes-oriented mindset with a focus on delivering measurable business and customer value.

• Strong analytical and problem-solving skills to inform decision-making at scale.

• Comfortable operating in dynamic environments and adapting strategy in response to change.

Get to know Syneos Health

Over the past 5 years, we have worked with 94% of all Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 Studies across 73,000 Sites and 675,000+ Trial patients.

No matter what your role is, you’ll take the initiative and challenge the status quo with us in a highly competitive and ever-changing environment. Learn more about Syneos Health.

Additional Information

Tasks, duties, and responsibilities as listed in this job description are not exhaustive. The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities. Equivalent experience, skills, and/or education will also be considered so qualifications of incumbents may differ from those listed in the Job Description. The Company, at its sole discretion, will determine what constitutes as equivalent to the qualifications described above. Further, nothing contained herein should be construed to create an employment contract. Occasionally, required skills/experiences for jobs are expressed in brief terms. Any language contained herein is intended to fully comply with all obligations imposed by the legislation of each country in which it operates, including the implementation of the EU Equality Directive, in relation to the recruitment and employment of its employees. The Company is committed to compliance with the Americans with Disabilities Act, including the provision of reasonable accommodations, when appropriate, to assist employees or applicants to perform the essential functions of the job.

Summary

The Principal Product Manager drives enterprise-level product strategy and outcomes for healthcare and life sciences products and capabilities, which may include software, technology-enabled, or data-enabled solutions. This role defines long-term product vision and strategy across multiple products or platforms, partners closely with executive leadership, and influences key business decisions through product insights. Operating with broad autonomy, the Principal Product Manager leads through influence, sets product standards and best practices, and ensures product investments deliver measurable customer and business impact in a regulated environment.