Global Technical Leader

Oxford Biomedica UK Limited
Durham, NC

OXB is a quality and innovation-led viral vector CDMO that enables its clients to deliver life-changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, OXB has more than 30 years of experience in viral vectors, the driving force behind the majority of gene therapies. Cell and gene therapy is the treatment of disease by the delivery of therapeutic genetic material (DNA or RNA), into a patient’s cells. One highly effective approach to delivering genetic information is to re-engineer existing viruses to be safe delivery vehicles (vectors) to insert the genetic material into patients’ cells. This can be achieved either by directly administering the vector to the patient (often referred to as in vivo gene therapy), or by first introducing the genetic material to cells or tissue outside of the body, before administering the cells or tissue into the patient (often referred to as ex vivo gene therapy or gene-modified cell therapy). OXB collaborates with some of the world's most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno-associated virus (AAV) and adenoviral vectors. OXB's world-class capabilities span from early-stage development to commercialisation. These capabilities are supported by robust quality-assurance systems, analytical methods and depth of regulatory expertise. Join Us in Changing Lives At OXB, our people are at the heart of everything we do. We’re on a mission to enable life-changing therapies to reach patients around the world—and we’re looking for passionate individuals who embody our core values every day: Responsible, Responsive, Resilient, and Respectful. We are currently recruiting for Global Technical Leader to join the team. The purpose of the role is to drive OXB’s technical leadership in viral vector CDMO by designing and delivering strategic initiatives, aligning cross‑functional stakeholders, and representing the company’s innovation and quality‑led capabilities to clients and the wider industry, playing a key part in advancing our mission and making a real difference. This role can be located close by one of our global locations in Oxford, UK, Bedford, MA or Durham, NC, US, or Strasbourg or Lyon in France. Your responsibilities in this role would be:

  • Support business development by engaging with prospects, delivering pitch materials, addressing LVV and AAV technical questions, and contributing to proposals and Statements of Work with SMEs.
  • Provide global oversight and alignment of OXB’s viral vector technology platforms (AAV, LVV and others), ensuring clear definition, communication and integration of process and analytical components.
  • Incorporate market dynamics, customer expectations and scientific insights into ongoing platform evolution.
  • Partner with Innovation, Process Development, Strategy and Global MSAT to drive the introduction and adoption of new technologies aligned to customer and industry trends.
  • Shape and maintain OXB’s service offering portfolio, ensuring it reflects internal capabilities, strategic direction and market needs.
  • Collaborate with Marketing and Business Development to develop effective platform and service communication strategies.
  • Ensure work packages offered to customers are fully aligned with platform definitions, internal capabilities and strategic evolution.
  • Act as CMC technical lead for late‑phase programs, guiding clients and internal teams to develop phase‑appropriate technical and scientific strategies.
  • Represent OXB externally at conferences, meetings and industry engagements, maintaining awareness of technical and sector innovations.
We are looking for:
  • Degree in a scientific or engineering discipline; postgraduate qualifications are an advantage.
  • Relevant industrial experience in viral vectors, gene therapy, biologics or related fields.
  • Strong technical expertise in viral vector CDMO technologies, including process unit operations, analytics, equipment, GMP and regulatory guidelines.
  • Solid understanding of regulatory frameworks (cGMP, ICH) and emerging CGT industry expectations.
  • Proven ability to drive new technical capabilities and continuous platform improvement.
  • Strong analytical and strategic thinking skills, with sound commercial awareness and problem‑solving capability.
  • Excellent communication and influencing skills, with the ability to engage credibly and effectively with senior internal stakeholders, clients, and external partners.
  • Strong interpersonal skills and the ability to work collaboratively, lead cross‑functional efforts and contribute to high‑performing team dynamics.
The US salary range for this position: $146k - $195 per year. This offer range represents the anticipated base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for performance-based bonuses. Benefits offered by OXB include health insurance, 401k contributions, paid time off (PTO) and tuition reimbursement. This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the United States. About Us: OXB is a quality and innovation-led viral vector CDMO with a mission to enable its clients to deliver life changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, we have more than 30 years of experience in viral vectors; the driving force behind the majority of gene therapies. OXB collaborates with some of the world’s most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno-associated virus (AAV) and adenoviral vectors. OXB’s world-class capabilities span from early-stage development to commercialisation. These capabilities are supported by robust quality-assurance systems, analytical methods, and depth of regulatory expertise. Why Join Us?
  • 💸 Competitive total reward packages
  • 🧘 Wellbeing programs that support your mental and physical health
  • 🚀 Career development opportunities to help you grow and thrive
  • 🤝 Supportive, inclusive, and collaborative culture
  • 🧪 State-of-the-art labs and manufacturing facilities
  • 🌍 A company that lives its values: Responsible, Responsive, Resilient, Respect
We want you to feel inspired every day. At OXB, we’re future-focused and growing fast. We succeed together—through passion, commitment, and teamwork. Ready to Make a Difference? Oxford Biomedica is a quality and innovation-led viral vector CDMO that enables its clients to deliver life-changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, Oxford Biomedica has more than 30 years of experience in viral vectors, the driving force behind the majority of gene therapies. Cell and gene therapy is the treatment of disease by the delivery of therapeutic genetic material (DNA or RNA), into a patient’s cells. One highly effective approach to delivering genetic information is to re-engineer existing viruses to be safe delivery vehicles (vectors) to insert the genetic material into patients’ cells. This can be achieved either by directly administering the vector to the patient (often referred to as in vivo gene therapy), or by first introducing the genetic material to cells or tissue outside of the body, before administering the cells or tissue into the patient (often referred to as ex vivo gene therapy or gene-modified cell therapy). Oxford Biomedica collaborates with some of the world's most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno-associated virus (AAV) and adenoviral vectors. Oxford Biomedica's world-class capabilities span from early-stage development to commercialisation. These capabilities are supported by robust quality-assurance systems, analytical methods and depth of regulatory expertise.

Posted 2026-05-11

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