Sr. Manager, Process Excellence

ProKidney Corp.
Winston Salem, NC
Position Summary:

As an Sr. Manager, Process Excellence, you will play a strategic role in driving efficiency, compliance, and transformation within Operational Excellence. You will guide cross-functional teams across manufacturing operations, fostering a culture of innovation, continuous improvement, and operational excellence. Leveraging your expertise in GMP compliance, process improvement methodologies, and digital manufacturing technologies, you will elevate manufacturing performance and drive strategic initiatives.

Responsibilities:

  • Develop and implement innovative process improvement strategies, leveraging digital technologies and GMP best practices to enhance efficiency and compliance.
  • Collaborate with cross-functional teams to assess and execute strategies that enhance process efficiency, reduce costs, and improve overall performance, align to organizational objectives.
  • Develop and maintain comprehensive process documentation (SOPs, process maps, work instructions, RACI).
  • Lead change management initiatives to support adoption of new processes and technologies.
  • Stay current on industry advancements, best practices, and emerging trends in manufacturing operations management.
  • Proactively identify opportunities for optimization, cost reduction, and value creation.
  • Identify opportunities for digital transformation within manufacturing operations (automation, data analytics, and tool integration).
  • Utilize data analytics and KPIs to monitor performance and identify trends, compliance issues, and improvement opportunities.
  • Produce clear reports and insights for senior leadership to inform strategic decisions and provide visibility into manufacturing performance.
  • Communicate effectively at all levels, translating complex concepts and strategies into actionable objectives.
  • Foster a culture of openness, transparency, and collaboration across manufacturing operations.

Qualifications:

  • Bachelor’s degree in Operations Management, Engineering, Life Sciences, or related field. Master’s degree or relevant certifications (e.g., Lean Six Sigma, PMP, CQE) preferred.
  • Minimum of 5 years of experience in manufacturing operations management, GMP compliance, process improvement, or related roles in a regulated environment.
  • Strong knowledge of GMP regulations and regulatory compliance requirements.
  • Expertise in Operational Excellence and continuous improvement methodologies (Lean, Six Sigma, VSM, DMAIC).
  • Proficient in process documentation, mapping, and RACI frameworks (SOPs, WI).
  • Familiarity with autologous aseptic manufacturing and cleanroom operations.
  • Proficiency with manufacturing digital technologies (ERP, MES, LIMS) and process analytics tools (Excel, Visio, data visualization software).
  • Knowledge of Chain of Identity/Chain of Custody is a plus.
  • Track record of inspection readiness and remediation is a plus.
  • Strong analytical, strategic thinking, and change management skills.
  • Executive presence with excellent communication skills across all organizational levels.

ProKidney is an equal employment opportunity employer and does not discriminate against any applicant because of race, creed, color, age, national origin, ancestry, religion, gender, sexual orientation, disability, genetic information, veteran status, military status, application for military service or any other class protected by state or federal law.

Applicants must be eligible to work in the United States without the need for work visa or residency sponsorship.
Posted 2026-02-20

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