Senior MES Engineer - Life Sciences / Pharma

BlackStar
Raleigh, NC

Senior MES Engineer – Life Sciences | Raleigh, NC (Hybrid, 25% Travel)

Salary: $145K–$180K Base + 20–35% Bonus

Location: Raleigh, North Carolina (Hybrid, 25% travel)

About the Role:
We are seeking a Senior MES Engineer with deep Life Sciences MES experience to lead complex projects, act as a solution architect , and mentor engineering teams. This role includes hands-on MES design, deployment, integration with ERP, LIMS, PLC/DCS, and historian systems , and ensuring regulatory compliance (cGMP, 21 CFR Part 11). You'll also have the opportunity to help establish and lead our Raleigh MES office .

Key Responsibilities:

  • Lead full lifecycle MES projects : concept, design, implementation, testing, and commissioning.
  • Deploy MES solutions using Werum PAS-X, Sepasoft, POMS or similar platforms.
  • Integrate MES with PLC/DCS, ERP (SAP), LIMS, Maximo, historians, and SQL/Oracle databases .
  • Ensure compliance with Life Sciences regulations and industry standards (GAMP5, S88/S95).
  • Act as technical lead and mentor , guiding engineers and technicians.
  • Support business development and client engagement, including trade shows and partnerships.
  • Manage budgets, schedules, and project profitability for projects up to $1M+.

Required Qualifications:

  • Must reside in North Carolina
  • 10+ years MES experience , with 4+ years in Life Sciences
  • Bachelor's degree in Engineering, Computer Science, or Applied Sciences
  • Proven expertise in MES platforms, industrial automation, systems integration, and relational databases
  • Leadership experience: managing teams and mentoring junior staff
  • Ability to travel up to 25%

Preferred Qualifications:

  • Integrator or consulting experience
  • Experience with whitefield and brownfield MES projects
  • Aptitude for business development and client relationship building

Why Join Us:

  • 100% Employee-Owned (ESOP) with 40+ years of industry expertise
  • ENR Top 500 Engineering Firm and a leading Life Sciences systems integrator
  • Opportunity to lead your own MES office in Raleigh
  • Work on high-profile, multi-office Life Sciences projects
Posted 2026-04-03

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