Senior MES Engineer - Life Sciences

We are seeking a Senior MES Engineer to lead and deliver cutting-edge Manufacturing Execution System (MES) solutions in the Life Sciences industry. This is a leadership role with a focus on software design, MES solution deployment, system integration, and project execution . The ideal candidate will act as a solution architect, mentor engineers, and oversee projects from concept to commissioning.

If you thrive in a collaborative environment, enjoy solving complex engineering challenges, and want the autonomy to lead your own MES office in North Carolina, this role is perfect for you.

Key Responsibilities:

• Lead MES projects across the full lifecycle: conceptual design, specification development, implementation, testing, start-up, and commissioning .
• Act as solution architect for MES deployments, integrating industrial processes with control, ERP, LIMS, and other systems (PLC/DCS, Historian, SQL/Oracle).
• Deliver whitefield and brownfield MES solutions that enhance operational efficiency, regulatory compliance, and productivity.
• Manage project planning, budgets, schedules, task prioritization, and reporting for projects up to $1M.
• Lead, mentor, and guide engineers and technicians in technical execution.
• Support business development initiatives, including trade shows, associations, and client engagement .
• Ensure MES solutions comply with Life Sciences regulations: cGMP, 21 CFR Part 11, GAMP5, S88, S95 .

Required Qualifications:

• Location: Must reside in North Carolina
• Experience: 8-10+ years in MES engineering, 4+ years in Life Sciences MES projects
• Expertise in Werum PAS-X, Sepasoft, or POMS MES platforms
• Proven experience in full MES project lifecycle (design, implementation, commissioning)
• Strong understanding of system integration across controls, ERP, LIMS, historian technologies, relational databases, and reporting systems
• Ability to conceptualize, design, and implement MES solutions independently
• Experience leading teams and acting as a technical lead or project manager on smaller projects
• Familiarity with Life Sciences regulations: cGMP, 21 CFR Part 11, GAMP5, S88, S95
• Aptitude for business development and ability to generate new client opportunities

Preferred Experience:

• Experience at an integrator or exposure to system integration firms
• Leadership experience with MES office operations or team management

Why Join Us:

• 100% Employee-Owned ESOP, be part of a company that values your contribution
• ENR Top 500 Engineering Firm with 40+ years of industry experience
• Opportunities for career growth and leadership in North Carolina
• Work on innovative MES solutions with national and international clients
• Competitive compensation and bonus potential

Work Model:

• Remote within North Carolina
• Travel up to 25%
• Opportunity to eventually lead MES office operations in NC